Crohn’s disease (CD) is a chronic and debilitating inflammatory bowel disease (IBD) affecting millions of individuals worldwide and steadily increasing in prevalence 1. Prolonged inflammation in CD ...

The heart and brain are among the earliest and most metabolically demanding organs in human development. Though historically studied in isolation, both ...

This Collection supports and amplifies research related to SDG 3 - Ensure healthy lives and promote well-being for all at all ages. Cancer research has hugely benefitted from the growth in single-cell ...

Plant immunity research has undergone a transformative shift with the advent of spatial and single-cell technologies, ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Advances in next-generation sequencing (NGS) technologies have lowered costs and reduced the complexity of DNA and RNA sequencing, enabling new possibilities when studying gene activity. In ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Kelly Parliament, staff application scientist at Beckman Coulter Life Sciences, discusses how automation is improving the efficiency of single-cell transcriptomic workflows. Single-cell ...

Why do so many promising drugs fail? This article explores how spatial multiomics reveals hidden cell interactions, helping ...

Over the past decades, lineage tracing has been fundamental to unraveling how diverse cell types arise during development and how tumors evolve ...

The renewed Single Cell and Spatial Omics Course provides an introduction to scRNA-seq and spatial omics principles and data analysis, covered by both lectures and hands-on sessions. Course overview ...