Recent advances in single-cell sequencing and spatial multi-omics have transformed our ability to resolve tumor ecosystems at unprecedented resolution.

Cancer is characterized by genetic evolution and cellular heterogeneity, which impact disease initiation, progression and ultimately therapeutic response. The various components of the tumor ...

Single-cell RNA sequencing (scRNA-seq) has become an indispensable tool in prostate biology research, considerably advancing our understanding from organ development to disease initiation and ...

Over the past decades, lineage tracing has been fundamental to unraveling how diverse cell types arise during development and how tumors evolve ...