Tumor resistance to chemotherapeutic drugs is a common problem that limits the efficacy of these drugs in the clinical setting. The mechanisms for how tumors develop resistance to chemotherapeutic ...
The tagged microarray marker (TAM) method allows high-throughput differentiation between predicted alternative PCR products. Typically, the method is used as a molecular marker approach to determining ...
RNA interference technology, which is used in cell biology, has revolutionized functional research of the gene products in the last ten years. Now researchers have developed a method which allows a ...
Here, we describe the optimization of a miniaturized cell spot microarray (CSMA) method, which facilitates utilization of the transfection microarray technique for disparate RNAi analyses. To promote ...
Division of Biology, OSEL/CDRH/FDA. Tuberculosis is the second leading cause of adult mortality among infectious diseases and is responsible for about 2 million deaths per year worldwide. The World ...
We developed a microarray-based system for screening small molecules in mammalian cells. This system is compatible with image-based screens and requires fewer than 100 cells per compound. Each ...
Abstract: There are many undesirable systematic variations in general microarray experiments. Normalization is the process of removing such variations which affect the measured gene expression levels.
Abstract: Segmentation or separation of spots from the background in cDNA microarray images is one of the earlier steps in gene expression data analysis. Performance of the segmentation method may ...
We are pleased to share with you the final version of our paper "A graph partitioning-based hybrid feature selection method in microarray datasets ". The paper is co ...