Incorporating space and time into models of cell fate transition will be a key step toward characterizing how interactions among neighboring cells, local niche factors and cell migration contribute to ...

In multicellular organisms, each cell is influenced by the others in its surrounding environment, and the maintenance of cellular and tissue spatiality – or lack thereof – carries significant ...

Spatial biology has rapidly reshaped tissue analysis, but most methods still rely on thin two-dimensional (2D) slices, giving fragmented glimpses of complex tissue structures. As spatial ...

Multicellular eukaryotic organisms, including plants, are characterized by diverse cell types and complex spatiotemporal patterns of gene expression. Although all cells within a plant share the same ...

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...

Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...

A collaborative project has created a comprehensive guide to help standardize spatial transcriptomics practices. Spatial transcriptomics provides a unique perspective on the genes that cells express ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...