Relapse to drug abuse is often caused by exposure to drug-associated cues that evoke craving. Therefore, disruption of the cue–drug memory can prevent relapse. Memories destabilize and become ...

Appetitive memories play a crucial role in learning and behavior, but under certain circumstances, such memories become maladaptive and play a vital role in addiction and other psychopathologies.

Version of Record: This is the final version of the article. The authors attempted to replicate previous work showing that counterconditioning leads to more persistent reduction of threat responses, ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

Let’s talk about counterconditioning. It might sound like a technical term, but the idea behind it is actually pretty simple. It’s all about changing how someone feels. Instead of focusing on stopping ...

For example, imagine if every time your dog saw a person walk by the house, they lunged at the window, growled, barked, and scratched up your windowsill. These negative feelings and unwanted behaviors ...