Cellular reprogramming is the hottest topic in longevity science, with tech titans like Sam Altman investing in it. It's now being tested in humans.

Scientists have taken a small but significant step toward testing the idea of reverse aging in humans. Researchers have ...

First human receives reverse-aging gene therapy in groundbreaking trial targeting glaucoma, using cellular reprogramming to make aged cells younger.

A groundbreaking human trial of ER-100, a cellular reprogramming therapy, has begun, testing whether damaged eye cells can be ...

World’s first anti-ageing gene therapy trial begins as ER-100 is injected into a human eye, testing partial cellular ...

Biotech startup NewLimit secures a major funding round after claiming a ‘breakthrough discovery’ of a prototype medicine that rewinds cellular aging in the liver.

Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only. This limits the potential use of adult cells for ...

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

On Dec. 2, 2020, the international journal Nature splashed the cover with a retinal image and the bold headline "Turning back time." A title more fitting for a movie or novel referred to a research ...

Aging, at its most fundamental level, is a molecular process. Chemical marks on the genome shift and lose fidelity over time, ...

Reprogramming often yields heterogeneous cell fates, yet the underlying mechanisms remain poorly understood. To address this, we developed single-cell transcription factor sequencing (scTF-seq), a ...

Cell-cell fusion is a biological process where two cells merge their membranes and cytoplasmic contents, forming a single hybrid cell 1. This fundamental event plays crucial roles in development, ...